Schistosoma mansoni lncRNAs Database



This site contains the web resource described in the paper "Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes" (2018) by Elton J. R. Vasconcelos, Vinícius C. Mesel, Lucas F. daSilva, David S. Pires, Guilherme M. Lavezzo, Adriana S. A. Pereira, Murilo S. Amaral and Sergio Verjovski-Almeida, Database, Volume 2018: bay068, https://doi.org/10.1093/database/bay068.


Based on data from Vasconcelos, EJR et al., The Schistosoma mansoni genome encodes thousands of long noncoding RNAs predicted to be functional at different parasite life-cycle stages. Scientific Reports 7: 10508, 2017.


Datasets Used

Fifteen RNA-Seq libraries were used in the SmLINCs-Smps expression correlation analyses as described in our previous work (Vasconcelos, E.J.R., daSilva, L.F., Pires, D.S., et al. (2017) The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages. Sci Rep, 7, 10508.) and represent the five life cycle stages: biological triplicates for cercariae (ERR022872, ERR022877 and ERR022878), somula 3h (ERR022874, ERR022876 and ERR022879), somula 24h (ERR022880, ERR022881 and ERR022882), male (SRR5170192, SRR5170191 and SRR5170190) and female (SRR5170180, SRR5170179 and SRR5170178) adults. The three former stages are from Protasio, A.V., Tsai, I.J., Babbage, A., et al. (2012) A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni. PLoS Negl Trop Dis, 6, e1455, while adult worm samples are from our group (NCBI BioProject ID: PRJNA361136).