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Schistosoma mansoni

>> Link to Schistosoma mansoni lncRNAs Database web resource

>> Link to Schistosoma mansoni Genome Browser

Papers with links to S. mansoni genome browser tracks:

Long non-coding RNAs are essential for Schistosoma mansoni pairing-dependent adult worm homeostasis and fertility.
Silveira, GO et al., PLoS Pathog 19(5): e1011369 (2023)

Single-cell RNA-seq analyses show that long non-coding RNAs are conspicuously expressed in Schistosoma mansoni gamete and tegument progenitor cell populations.
Morales-Vicente, D et al., Front. Genet. 13:924877 (2022)
>> Link to G16045 Locus tracks.
>> Link to G39666 Locus tracks.
>> Link to lncRNAs Database web resource

Rhesus macaques self-curing from a schistosome infection can display complete immunity to challenge
Amaral, MS et al.. Nature Communications, 12:6181 (2021).
>> Link to ChIP-Seq genome tracks.

Long non-coding RNAs as possible therapeutic targets in protozoa, and in Schistosoma and other helminths
Silveira, GO et al., Parasitology Research 121: 1091–1115 (2022)
doi: 10.1007/s00436-021-07384-5
>> Click here for pdf version of this paper
>> Link to S. mansoni lncRNA SmLINC156349 track

Assessment of reference genes at six different developmental stages of Schistosoma mansoni for quantitative RT-PCR
Silveira, GO et al., Scientific Reports 11, 16816 (2021)
>> Click here for expression data

Long non-coding RNA levels can be modulated by 5-Azacytidine in Schistosoma mansoni
Amaral, MS et al.. Scientific Reports 10:21565 (2020)
>> Download annotation.

Dynamic Expression of Long Non-Coding RNAs Throughout Parasite Sexual and Neural Maturation in Schistosoma japonicum
Lucas F. Maciel, David A. Morales-Vicente and Sergio Verjovski-Almeida.
Non-coding RNA 6(2):15 (2020)
doi: 10.3390/ncrna6020015
>> Download genomic annotation of lncRNAs.

Weighted gene co-expression analyses point to long non-coding RNA hub genes at different Schistosoma mansoni life-cycle stages
Maciel, LF et al., Front. Genet. 10:823 (2019)
doi: 10.3389/fgene.2019.00823
>> Click Here for locus view for this paper
>> Download annotation, reference and expression files of libraries used for this paper.

Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism
Pereira, ASA et al., PLoS Negl Trop Dis 12:e0006873 (2018)
doi: 10.1371/journal.pntd.0006873
>> Click here for locus view for this paper.
>> Download transcriptome and reference files for GSK343.

Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes
Vasconcelos, EJR et al., Database 2018:bay068 (2018)
doi: 10.1093/database/bay068
>> Click here for locus view for this paper.
>> Schistosoma mansoni lncRNAs Database web resource.

The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages
Vasconcelos, EJR et al., Scientific Reports 7:10508(2017)
doi: 10.1038/s41598-017-10853-6
>> Click here for locus view for this paper.

Human LNCaP ARA-lincRNAs

Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the Loci of Non-associated LincRNAs
DaSilva, LF et al., Front. Genet. 9:132 (2018)
doi: 10.3389/fgene.2018.00132
>> UCSC Genome Browser ARA-lincRNAs [Custom Tracks]
>> Download tracks and annotation